Periodontal disease (also known as gum disease) is a chronic inflammatory condition that not only affects oral health but has been scientifically linked to various systemic health problems. These connections often stem from inflammation, bacterial spread, or shared risk factors like smoking and poor hygiene. Below is a curated list of key associated conditions, based on established research.

• Cardiovascular Disease (including Heart Disease and Stroke): The inflammation and bacteria from periodontal disease can enter the bloodstream, contributing to artery plaque buildup and increasing the risk of heart attacks or strokes.
• Diabetes (Type 2): There’s a bidirectional relationship—poorly controlled diabetes worsens gum disease, while gum disease impairs blood sugar control, raising complication risks.
• Respiratory Diseases (e.g., Pneumonia): Oral bacteria can be inhaled into the lungs, exacerbating infections, especially in vulnerable groups like the elderly.
• Adverse Pregnancy Outcomes (e.g., Preterm Birth, Low Birth Weight, Stillbirth): Periodontal inflammation releases toxins that may trigger early labor or affect fetal development.
• Rheumatoid Arthritis: Shared inflammatory pathways link gum disease to joint inflammation and autoimmune responses.
• Alzheimer’s Disease and Cognitive Decline: Bacteria from infected gums may travel to the brain. Tooth loss correlates with faster cognitive deterioration.
• Cancer (e.g., Lung, Colorectal, Pancreatic): Chronic inflammation from periodontitis may promote tumor growth or metastasis, with studies showing up to 50% higher risk for certain types.
• Osteoporosis: Bone loss in the jaw from gum disease mirrors systemic bone density reduction, potentially accelerating osteoporosis progression.
• Kidney Disease: Inflammatory markers from periodontal disease can strain kidney function, worsening chronic kidney issues.
• Dementia: Similar to Alzheimer’s, gum disease bacteria and inflammation are implicated in broader neurodegenerative changes.